Paternal Age Effect: How Old is Too Old?
Growing evidence shows that the health of offspring of older fathers is at risk. Paternal age of 35 is advanced.Paternal age is the major source of de novo genetic disorders. The rise in offspring with "autism" is expected as paternal age rises. Alzheimer's, schizophrenia,autoimmune disorders are increasing.
Monday, March 24, 2014
Saturday, March 22, 2014
Link between father’s age and schizophrenia discovered REDISCOVERED!
Monday, March 03, 2014
Children of older men have greater risk of mental illness
BBC News | 27 February 2014
The Guardian | 26 February 2014
EurekAlert! (press release) | 26 February 2014
New York Times | 26 February 2014
JAMA Psychiatry | 26 February 2014
Sunday, March 02, 2014
The Benefits of Curcumin in Cancer Treatment
We see that there's actually quite a large amount of evidence that supports using various molecules, natural products, and pharmaceuticals that are already approved and that have been around for a long time to affect anti-cancer activity along that pathway at that target. That's called molecularly targeted anti-cancer treatment, and it's widely practiced in oncology today.
Inhibit the proliferation of tumor cells
Inhibit the transformation of cells from normal to tumor
Inhibit the synthesis of a protein thought to be instrumental in tumor formation
Help your body destroy mutated cancer cells so they cannot spread throughout your body
Help prevent the development of additional blood supply necessary for cancer cell growth (angiogenesis)
Saturday, March 01, 2014
Friday, February 28, 2014
Thursday, February 27, 2014
Largest, Longest Study on Mammograms Again Finds No Benefit
An annual mammogram is the conventional go-to "prevention" strategy for breast cancer. But researchers increasingly agree that mammography is ineffective at best and harmful at worst.
At this point, the controversy is pretty much settled—at least if you take the published research into account. To all of my opponents out there who have attacked me for my opinion regarding mammograms, I know they will remain in denial. The big lie must continue to be told to avoid the guilt associated with the damage done. The attacks only make us better at defending controversial views.
- In 2007, the Archives of Internal Medicine7 published a meta-analysis of 117 randomized, controlled mammogram trials. Among its findings: rates of false-positive results are high (20-56 percent after 10 mammograms)
- Similar results were found in a 2009 meta-analysis by the Cochrane Database Review,8 which found that breast cancer screening led to a 30 percent rate of overdiagnosis and overtreatment, which actually increased the absolute risk of developing cancer by 0.5 percent. The review concluded that for every 2,000 women invited for screening throughout a 10-year period, the life of just ONE woman was prolonged, while 10 healthy women were treated unnecessarily.
- Another Norwegian study,9 published in 2010, concluded that the reduction in mortality as a result of mammographic screening was so small as to be nonexistent—a mere 2.4 deaths per 100,000 person-years were spared as a result of the screening.
- Research published in The Lancet Oncology in 2011,10 described the natural history of breast cancers detected in the Swedish mammography screening program between 1986 to 1990, involving 650,000 women. Since breast lesions and tumors are aggressively treated and/or removed before they can be determined with any certainty to be a clear and present threat to health, there has been little to no research on what happens when they are left alone.
- This study however, demonstrated for the first time that women who received the most breast screenings had a higher cumulative incidence of invasive breast cancer over the following six years than the control group who received far less screenings.
- Avoid sugar, especially fructose, and processed foods. All forms of sugar are detrimental to health in general and promote cancer. Refined fructose, however, is clearly one of the most harmful and should be avoided as much as possible. This automatically means avoiding processed foods, as most are loaded with fructose (typically in the form of high fructose corn syrup, HFCS).
- Optimize your vitamin D levels. Vitamin D influences virtually every cell in your body and is one of nature's most potent cancer fighters. Vitamin D is actually able to enter cancer cells and trigger apoptosis (cell death). If you have cancer, your vitamin D level should probably be between 70 and 100 ng/ml. Vitamin D works synergistically with every cancer treatment I'm aware of, with no adverse effects. Ideally, your levels should reach this point by exposure to the sun or a safe tanning bed, not oral vitamin D.
- Limit your protein. Newer research has emphasized the importance of the mTOR pathways. When these are active, cancer growth is accelerated. One way to quiet this pathway is by limiting your protein to one gram of protein per kilogram of lean body mass, or roughly a bit less than half a gram of protein per every pound of lean body weight. For most people this ranges between 40 and 70 grams of protein a day, which is typically about 2/3 to half of what they are currently eating.
- Avoid unfermented soy products. Unfermented soy is high in plant estrogens, or phytoestrogens, also known as isoflavones. In some studies, soy appears to work in concert with human estrogen to increase breast cell proliferation, which increases the chances for mutations and cancerous cells.
- Improve your insulin and leptin receptor sensitivity. The best way to do this is by avoiding sugar and grains and restricting carbs to mostly fiber vegetables. Also make sure you are exercising, especially with Peak Fitness.
- Exercise regularly. One of the primary reasons exercise works to lower your cancer risk is because it drives your insulin levels down, and controlling your insulin levels is one of the most powerful ways to reduce your cancer risks. It's also been suggested that apoptosis (programmed cell death) is triggered by exercise, causing cancer cells to die. Studies have also found that the number of tumors decrease along with body fat, which may be an additional factor. This is because exercise helps lower your estrogen levels, which explains why exercise appears to be particularly potent against breast cancer.
- Maintain a healthy body weight. This will come naturally when you begin eating right for your nutritional type and exercising. It's important to lose excess body fat because fat produces estrogen.
- Drink a pint to a quart of organic green vegetable juice daily. Please review my juicing instructions for more detailed information.
- Get plenty of high-quality, animal-based omega-3 fats, such as krill oil. Omega-3 deficiency is a common underlying factor for cancer.
- Curcumin. This is the active ingredient in turmeric and in high concentrations can be very useful adjunct in the treatment of cancer. It actually has the most evidence-based literature18 supporting its use against cancer of any nutrient, including vitamin D. For example, it has demonstrated major therapeutic potential in preventing breast cancer metastasis.19 It's important to know that curcumin is generally not absorbed that well, so I've provided several absorption tips here. Newer preparations have also started to emerge, offering better absorption. For best results, you'll want to use a sustained release preparation.
- Avoid drinking alcohol, or at least limit your alcoholic drinks to one per day.
- Avoid electromagnetic fields as much as possible. Even electric blankets can increase your cancer risk.
- Avoid synthetic hormone replacement therapy, especially if you have risk factors for breast cancer. Breast cancer is an estrogen-related cancer, and according to a study published in the Journal of the National Cancer Institute, breast cancer rates for women dropped in tandem with decreased use of hormone replacement therapy. (There are similar risks for younger women who use oral contraceptives. Birth control pills, which are also comprised of synthetic hormones, have been linked to cervical and breast cancers.)
- If you are experiencing excessive menopausal symptoms, you may want to consider bioidentical hormone replacement therapy instead, which uses hormones that are molecularly identical to the ones your body produces and do not wreak havoc on your system. This is a much safer alternative.
- Avoid BPA, phthalates, and other xenoestrogens. These are estrogen-like compounds that have been linked to increased breast cancer risk.
- Make sure you're not iodine deficient, as there's compelling evidence linking iodine deficiency with certain forms of cancer. Dr. David Brownstein,20 author of the book Iodine: Why You Need It, Why You Can't Live Without It, is a proponent of iodine for breast cancer. It actually has potent anticancer properties and has been shown to cause cell death in breast and thyroid cancer cells.
- For more information, I recommend reading Dr. Brownstein's book. I have been researching iodine for some time ever since I interviewed Dr. Brownstein as I do believe that the bulk of what he states is spot on. However, I am not at all convinced that his dosage recommendations are correct. I believe they are far too high.
- Avoid charring your meats. Charcoal or flame-broiled meat is linked with increased breast cancer risk. Acrylamide—a carcinogen created when starchy foods are baked, roasted, or fried—has been found to increase cancer risk as well.
Anam Thubten and others teaching at the Vajrayana Foundation
Older Fathers Linked To Higher Risk Of Cognitive, Behavioral Issues In Their Offspring
Narcotic Pain Killers Deadly