Tuesday, November 28, 2006

I'm a complementary therapist and would certainly reccommend that the earlier, (within reason), you can have your children the better. Preferably in your twenties. I know some people disagree, but that's my opinion.
Jon

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Wednesday, November 22, 2006

James F. Crow as men age their sperm have more and more mutations

http://www.pnas.org/cgi/content/full/94/16/8380
When I'm not in class or in lab, I'm attending a seminar. Today's speaker James F. Crow gave a lecture on population genetics. His talk was remarkably coherent considering that the only genetics lectures I attended before were undergraduate classes taught by quirky professors who had the knack of zonking me out one-third of the way through despite their surreal humor.

I found this interesting: He concluded that many diseases caused by mutations in offspring were the result of fertile old men. His rationale was that the gametes of older men had gone through more cell divisions. More cell divisions mean more mutations since it increases the chance that there is a mistake whenever the genome divides. For women, it's different. By the time a female is born, all the eggs that she will ever produce during her lifetime are already present in the ovary.

A woman in the audience wondered about the social implications of this observation and inquired whether or not Dr. Crow was considering on pitching a proposal to Congress to discourage men 40 or over to not have children. Dr. Crow had no comment on that particular question.

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Saturday, November 18, 2006

Amber Light of Male Reproductive Health

http://www.theaustralian.news.com.au/story/0,20867,20394126-38940,00.html http://www.andrologyjournal.org/cgi/content/full/24/4/459?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=thonneau&searchid=1140778679297_10&FIRSTINDEX=0&journalcode=jandrol

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Wednesday, November 15, 2006

Penrose AND Advanced Paternal Age

http://www.genetics.org/cgi/content/full/150/4/1333
Lionel Sharples Penrose First to prove the connection between advanced paternal age and serious problems in offspring.

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Monday, November 13, 2006

If all babies had fathers less than 30, the paper suggests the incidence of schizophrenia would reduce by at least 15%

Like the discovery of the connection between mothers over 35 and Down Syndrome Swedish Research that tracked over 700,000 young people published in 2004.



There is a "strong association" between men who become fathers after the age of 50 and of schizophrenia in their children, a study has found.

Swedish research that tracked over 700,000 young people found 15 per cent of schizophrenia cases could be attributed to older fathers. Researchers believe the link may be due to sperm mutations, which accumulate as men get older.

Compared with men who become fathers between 21 and 24, those who father children at the age of 50 or older have four to five times the chance of their offspring developing schizophrenia. The link was stronger if there was no family history of the disorder.

The link between schizophrenia and older paternity had been made before, but this was the first large study to look at a range of factors that could confound the results, said Professor John McGrath, a psychiatric epidemiologist at the Queensland Centre for Mental Health Research.

"If all babies had fathers less than 30, the paper suggests, the incidence of schizophrenia would reduce by 15 per cent," he said.

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Saturday, November 11, 2006

Scientists studying male reproduction not believed and their research not publicized

Read Exposing Men: The Science and Politics of Male Reproduction, Oxford University Press, Cynthia Daniels, Asst. Professor of Political Science at Rutgers University

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