Nat Rev Endocrinol. 2013 Jul 9. doi: 10.1038/nrendo.2013.141. [Epub ahead of print] Growth and development: Paternal age and offspring outcomes. [No authors listed] PMID: 23835369 [PubMed - as supplied by publisher]
Growing evidence shows that the health of offspring of older fathers is at risk. Paternal age of 35 is advanced.Paternal age is the major source of de novo genetic disorders. The rise in offspring with "autism" is expected as paternal age rises. Alzheimer's, schizophrenia,autoimmune disorders are increasing.