Monday, January 15, 2007

"I noticed that many children with schizophrenia had old fathers" Christina Dallman physician

Father's age raises schizophrenia risk

September 06 2002 at 06:55PM

Stockholm - Swedish scientists have found that older men face a much greater risk of fathering schizophrenic children than younger men.

Schizophrenia is a widespread and debilitating form of mental disease with symptoms ranging from delusions and an altered sense of self to apathy and social withdrawal.

Scientists at Sweden's Karolinska Institute found that children fathered by men aged 45 or older were three times as likely to develop schizophrenia as offspring of men aged 20-24.

"We already knew there was an increased risk when older women have children," Christina Dahlman, the physician who led the study, said.

"When I looked closer at the men, I noticed that many children with schizophrenia had old fathers."

The findings, released this week, support earlier studies by Israeli and American scientists.

As in many Western countries, couples in Sweden are delaying having their first child. In the past three decades, the average age of a first-time mother has risen by five years to 28,5 years.

Dahlman and colleague Peter Allebeck studied 524 schizophrenics for more than seven years and found that being fathered by an older man doubled the risk of developing the disease.

As most older men tended to have older wives, the cumulative risk was three times greater.

The reasons for the link were unclear, but Dahlman said sperm cell mutations, which increase with a man's age, have been known to cause various other diseases.

Children of older men may also lose their fathers at an early age, possibly increasing the risk of schizophrenia.

Around 24 million people worldwide suffer from schizophrenia, according to the World Health Organisation. Symptoms can be treated but there is no cure.

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At 4:23 PM , Blogger Cat's Experiment said...

thanks for your is time for men to understand their place in the's not all about the female!

At 8:29 PM , Blogger concerned heart said...

So much suffering is a caused by men not knowing that the male biological clock peaks at 30 and he mental health of offspring suffer as men father babies at older ages on population level. Study after study for 50 years shows increased mental illness, cancers, Alzheimer's, autoimmune disorders in offspring as a man ages and his Sperm stem cell's DNA and imprinting abilities mutate with each of hundreds and hundreds of divisions from the precursor genes. Each division leads to mutations-ovum do not divide many times until fertilization so it is is the male germ line that is responsibile for 1/3 or more new non familial cases of mental illness etc. Young males should pick older experienced females healthy babies like the chimps do.35 and up is considered older despite what the mass media and misleading science wants one to believe. It is the age of the father and not the age of the mother that is crucial or the age of the maternal grandFATHER that is crucial for the health of future generations.


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